Frequency and methylation status of selected retrotransposition competent L1 loci in amyotrophic lateral sclerosis

Long interspersed element-1 (LINE-1/L1) is the only autonomous transposable element in the human genome that currently mobilises in both germline and somatic tissues. Recent studies have identified correlations between altered retrotransposon expression and the fatal neurodegenerative disease amyotr...

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Detalles Bibliográficos
Autores principales: Savage, Abigail L., Lopez, Ana Illera, Iacoangeli, Alfredo, Bubb, Vivien J., Smith, Bradley, Troakes, Claire, Alahmady, Nada, Koks, Sulev, Schumann, Gerald G., Al-Chalabi, Ammar, Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666467/
https://www.ncbi.nlm.nih.gov/pubmed/33187550
http://dx.doi.org/10.1186/s13041-020-00694-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666467/
https://www.ncbi.nlm.nih.gov/pubmed/33187550
http://dx.doi.org/10.1186/s13041-020-00694-2

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