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Different transcriptional responses of haploid and diploid S. cerevisiae strains to changes in cofactor preference of XR

BACKGROUND: Xylitol accumulation is a major barrier for efficient ethanol production through heterologous xylose reductase-xylitol dehydrogenase (XR-XDH) pathway in recombinant Saccharomyces cerevisiae. Mutated NADH-preferring XR is usually employed to alleviate xylitol accumulation. However, it rem...

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Detalles Bibliográficos
Autores principales: Xie, Cai-Yun, Yang, Bai-Xue, Song, Qing-Ran, Xia, Zi-Yuan, Gou, Min, Tang, Yue-Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666519/
https://www.ncbi.nlm.nih.gov/pubmed/33187525
http://dx.doi.org/10.1186/s12934-020-01474-2