Maternal sitagliptin treatment attenuates offspring glucose metabolism and intestinal proinflammatory cytokines IL-6 and TNF-α expression in male rats

Increasing evidence shows that maternal overnutrition may increase the risk of diabetes in offspring. We hypothesized that maternal sitagliptin intervention may improve glucose intolerance through gut targeting. Female Sprague-Dawley (SD) rats were fed a normal diet (ND) or a high-fat diet (HFD) for...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Xiao, Xinhua, Zheng, Jia, Li, Ming, Yu, Miao, Ping, Fan, Wang, Tong, Wang, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Diabetes and Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666563/
https://www.ncbi.nlm.nih.gov/pubmed/33240638
http://dx.doi.org/10.7717/peerj.10310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666563/
https://www.ncbi.nlm.nih.gov/pubmed/33240638
http://dx.doi.org/10.7717/peerj.10310

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