Mir-141-3p Regulates Apoptosis and Mitochondrial Membrane Potential via Targeting Sirtuin1 in a 1-Methyl-4-Phenylpyridinium in vitro Model of Parkinson's Disease

OBJECTIVES: Parkinson's disease (PD) is a common neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons in the substantia nigra. The present study investigated miR-141-3p/sirtuin1 (SIRT1) activity in a 1-methyl-4-phenylpyridinium- (MPP+-) induced PC12-cell model of...

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Detalles Bibliográficos
Autores principales: Zheng, Yumin, Dong, Li, Liu, Na, Luo, Xiaoguang, He, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666638/
https://www.ncbi.nlm.nih.gov/pubmed/33204711
http://dx.doi.org/10.1155/2020/7239895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666638/
https://www.ncbi.nlm.nih.gov/pubmed/33204711
http://dx.doi.org/10.1155/2020/7239895

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