Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes

BACKGROUND: Gliomas evade current therapies through primary and acquired resistance and the effect of temozolomide is mainly restricted to methylguanin‐O6-methyltransferase promoter (MGMT) promoter hypermethylated tumors. Further resistance markers are largely unknown and would help for better strat...

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Detalles Bibliográficos
Autores principales: Kessler, Tobias, Berberich, Anne, Sadik, Ahmed, Sahm, Felix, Gorlia, Thierry, Meisner, Christoph, Hoffmann, Dirk C., Wick, Antje, Kickingereder, Philipp, Rübmann, Petra, Bendszus, Martin, Opitz, Christiane, Weller, Michael, van den Bent, Martin, Stupp, Roger, Winkler, Frank, Brandes, Alba, von Deimling, Andreas, Platten, Michael, Wick, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666733/
https://www.ncbi.nlm.nih.gov/pubmed/32991787
http://dx.doi.org/10.1002/cam4.3447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666733/
https://www.ncbi.nlm.nih.gov/pubmed/32991787
http://dx.doi.org/10.1002/cam4.3447

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