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Tim-3 promotes cell aggressiveness and paclitaxel resistance through NF-κB/STAT3 signalling pathway in breast cancer cells

OBJECTIVE: Although T-cell immunoglobulin and mucin-domain containing molecule-3 (Tim-3) has been recognized as a promising target for cancer immunotherapy, its exact role in breast cancer has not been fully elucidated. METHODS: Tim-3 gene expression in breast cancer and its prognostic significance...

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Detalles Bibliográficos
Autores principales: Cong, Yizi, Cui, Yuxin, Zhu, Shiguang, Cao, Jianqiao, Zou, Haidong, Martin, Tracey A., Qiao, Guangdong, Jiang, Wenguo, Yu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666787/
https://www.ncbi.nlm.nih.gov/pubmed/33223752
http://dx.doi.org/10.21147/j.issn.1000-9604.2020.05.02