The rs78378222 prevalence and the copy loss of the protective allele A in the tumor tissue of diffuse large B-cell lymphoma

BACKGROUND: Rare single nucleotide polymorphisms (SNPs) are likely to be a crucial genetic factor for human diseases, including cancer. rs78378222 is rare SNP in 3′-untranslated region (UTR) of TP53 gene leading to disturbance of 3′-end mRNA processing. The frequency of rs78378222 varies in several...

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Detalles Bibliográficos
Autores principales: Voropaeva, Elena N., Orlov, Yuriy L., Pospelova, Tatiana I., Gurageva, Anna A., Voevoda, Mikhail I., Maksimov, Vladimir N., Seregina, Olga B., Churkina, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666812/
https://www.ncbi.nlm.nih.gov/pubmed/33240649
http://dx.doi.org/10.7717/peerj.10335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666812/
https://www.ncbi.nlm.nih.gov/pubmed/33240649
http://dx.doi.org/10.7717/peerj.10335

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