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The rs78378222 prevalence and the copy loss of the protective allele A in the tumor tissue of diffuse large B-cell lymphoma
BACKGROUND: Rare single nucleotide polymorphisms (SNPs) are likely to be a crucial genetic factor for human diseases, including cancer. rs78378222 is rare SNP in 3′-untranslated region (UTR) of TP53 gene leading to disturbance of 3′-end mRNA processing. The frequency of rs78378222 varies in several...
Autores principales: | Voropaeva, Elena N., Orlov, Yuriy L., Pospelova, Tatiana I., Gurageva, Anna A., Voevoda, Mikhail I., Maksimov, Vladimir N., Seregina, Olga B., Churkina, Maria I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7666812/ https://www.ncbi.nlm.nih.gov/pubmed/33240649 http://dx.doi.org/10.7717/peerj.10335 |
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