A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity

Affordable and effective antiviral therapies are needed worldwide, especially against agents such as dengue virus that are endemic in underserved regions. Many antiviral compounds have been studied in cultured cells but are unsuitable for clinical applications due to pharmacokinetic profiles, side e...

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Detalles Bibliográficos
Autores principales: Moshiri, Jasmine, Constant, David A., Liu, Bowen, Mateo, Roberto, Kearnes, Steven, Novick, Paul, Prasad, Ritika, Nagamine, Claude, Pande, Vijay, Kirkegaard, Karla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667029/
https://www.ncbi.nlm.nih.gov/pubmed/33173007
http://dx.doi.org/10.1128/mBio.02839-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667029/
https://www.ncbi.nlm.nih.gov/pubmed/33173007
http://dx.doi.org/10.1128/mBio.02839-20

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