Cargando…
A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity
Affordable and effective antiviral therapies are needed worldwide, especially against agents such as dengue virus that are endemic in underserved regions. Many antiviral compounds have been studied in cultured cells but are unsuitable for clinical applications due to pharmacokinetic profiles, side e...
Autores principales: | Moshiri, Jasmine, Constant, David A., Liu, Bowen, Mateo, Roberto, Kearnes, Steven, Novick, Paul, Prasad, Ritika, Nagamine, Claude, Pande, Vijay, Kirkegaard, Karla |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667029/ https://www.ncbi.nlm.nih.gov/pubmed/33173007 http://dx.doi.org/10.1128/mBio.02839-20 |
Ejemplares similares
-
SWEETLEAD: an In Silico Database of Approved Drugs, Regulated Chemicals, and Herbal Isolates for Computer-Aided Drug Discovery
por: Novick, Paul A., et al.
Publicado: (2013) -
Targeting intramolecular proteinase NS2B/3 cleavages for trans-dominant inhibition of dengue virus
por: Constant, David A., et al.
Publicado: (2018) -
Suppression of Drug Resistance in Dengue Virus
por: Mateo, Roberto, et al.
Publicado: (2015) -
THPdb: Database of FDA-approved peptide and protein therapeutics
por: Usmani, Salman Sadullah, et al.
Publicado: (2017) -
FDA Approvals of Biologics in 2022
por: Martins, Alexander C., et al.
Publicado: (2023)