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Impact of Nuclear Export Pathway on Cytoplasmic HIV-1 RNA Transport Mechanism and Distribution

HIV-1 full-length RNA (referred to as HIV-1 RNA here) serves as the viral genome in virions and as a template for Gag/Gag-Pol translation. We previously showed that HIV-1 RNA, which is exported via the CRM1 pathway, travels in the cytoplasm mainly through diffusion. A recent report suggested that th...

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Detalles Bibliográficos
Autores principales: Chen, Jianbo, Umunnakwe, Chijioke, Sun, David Q., Nikolaitchik, Olga A., Pathak, Vinay K., Berkhout, Ben, Das, Atze T., Hu, Wei-Shau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667035/
https://www.ncbi.nlm.nih.gov/pubmed/33172997
http://dx.doi.org/10.1128/mBio.01578-20