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AdeABC Efflux Pump Controlled by AdeRS Two Component System Conferring Resistance to Tigecycline, Omadacycline and Eravacycline in Clinical Carbapenem Resistant Acinetobacter nosocomialis

Carbapenem-resistant Acinetobacter nosocomialis (CRAn) is a significant public health concern. Tigecycline non-susceptible CRAn (Tn-CRAn) isolates have emerged worldwide. Tigecycline resistance is mainly related to the overexpression of AdeABC efflux pump controlled by AdeRS two-component system (TC...

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Detalles Bibliográficos
Autores principales: Lee, Yi-Tzu, Chen, Hsing-Yu, Yang, Ya-Sung, Chou, Yu-Ching, Chang, Tein-Yao, Hsu, Wei-Jane, Lin, I-Chieh, Sun, Jun-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667285/
https://www.ncbi.nlm.nih.gov/pubmed/33224122
http://dx.doi.org/10.3389/fmicb.2020.584789