Novel Small Molecules against Two Binding Sites of Wnt2 Protein as potential Drug Candidates for Colorectal Cancer: A Structure Based Virtual Screening Approach

Wnts are the major ligands responsible for activating Wnt signaling pathway through binding to Frizzled proteins (Fzd) as the receptors. Among these ligands, Wnt2 plays the main role in the tumorigenesis of several human cancers especially colorectal cancer (CRC). Therefore, it can be considered as...

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Detalles Bibliográficos
Autores principales: Kalhor, Hourieh, Rahimi, Hamzeh, Akbari Eidgahi, Mohammad Reza, Teimoori-Toolabi, Ladan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667561/
https://www.ncbi.nlm.nih.gov/pubmed/33224221
http://dx.doi.org/10.22037/ijpr.2019.15297.13037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667561/
https://www.ncbi.nlm.nih.gov/pubmed/33224221
http://dx.doi.org/10.22037/ijpr.2019.15297.13037

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