Suvorexant, a Dual Orexin Receptor Antagonist, Protected Seizure through Interaction with GABA(A) and Glutamate Receptors

Orexin can increase neuronal excitability and induce epileptic activity. In this study, the effects of suvorexant (orexin receptor antagonist) on pentylenetetrazol (PTZ) and maximal electroshock (MES)-induced seizure were investigated. Mice were divided into 5 groups of six animals each including no...

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Detalles Bibliográficos
Autores principales: Razavi, Bibi Marjan, Farivar, Omid, Etemad, Leila, Hosseinzadeh, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667563/
https://www.ncbi.nlm.nih.gov/pubmed/33224245
http://dx.doi.org/10.22037/ijpr.2019.14688.12584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667563/
https://www.ncbi.nlm.nih.gov/pubmed/33224245
http://dx.doi.org/10.22037/ijpr.2019.14688.12584

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