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The Compelling Demand for an Effective PrP(C)-Directed Therapy against Prion Diseases

[Image: see text] Decades of research efforts have conclusively provided overwhelming evidence that the cellular prion protein (PrP(C)) plays a central role in prion diseases, a set of fatal and incurable neurodegenerative disorders for which no therapy is yet available. In this Viewpoint, we provid...

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Detalles Bibliográficos
Autores principales: Astolfi, Andrea, Spagnolli, Giovanni, Biasini, Emiliano, Barreca, Maria Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667650/
https://www.ncbi.nlm.nih.gov/pubmed/33209189
http://dx.doi.org/10.1021/acsmedchemlett.0c00528