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In situ tuning proangiogenic factor-mediated immunotolerance synergizes the tumoricidal immunity via a hypoxia-triggerable liposomal bio-nanoreactor

Rationale: Vascular abnormality stemming from the hypoxia-driven elevation of proangiogenic factors is a hallmark for many solid malignant tumors, including colorectal cancer (CRC) and its liver metastasis. We report a hypoxia-triggered liposome-supported metal-polyphenol-gene bio-nanoreactor to tun...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Zhang, Shengchang, Zhang, Rui, Sun, Peng, Shi, Chongdeng, Abdalla, Mohnad, Li, Anning, Xu, Jiawen, Du, Wei, Zhang, Jing, Liu, Ying, Tang, Chunwei, Yang, Zhenmei, Jiang, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667679/
https://www.ncbi.nlm.nih.gov/pubmed/33204325
http://dx.doi.org/10.7150/thno.50806