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In situ tuning proangiogenic factor-mediated immunotolerance synergizes the tumoricidal immunity via a hypoxia-triggerable liposomal bio-nanoreactor
Rationale: Vascular abnormality stemming from the hypoxia-driven elevation of proangiogenic factors is a hallmark for many solid malignant tumors, including colorectal cancer (CRC) and its liver metastasis. We report a hypoxia-triggered liposome-supported metal-polyphenol-gene bio-nanoreactor to tun...
Autores principales: | Chen, Chen, Zhang, Shengchang, Zhang, Rui, Sun, Peng, Shi, Chongdeng, Abdalla, Mohnad, Li, Anning, Xu, Jiawen, Du, Wei, Zhang, Jing, Liu, Ying, Tang, Chunwei, Yang, Zhenmei, Jiang, Xinyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667679/ https://www.ncbi.nlm.nih.gov/pubmed/33204325 http://dx.doi.org/10.7150/thno.50806 |
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