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AhR activation attenuates calcium oxalate nephrocalcinosis by diminishing M1 macrophage polarization and promoting M2 macrophage polarization

Calcium oxalate (CaOx) crystal can trigger kidney injury, which contributes to the pathogenesis of nephrocalcinosis. The phenotypes of infiltrating macrophage may impact CaOx-mediated kidney inflammatory injury as well as crystal deposition. How aryl hydrocarbon receptor (AhR) regulates inflammation...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoqi, Liu, Haoran, Ye, Tao, Duan, Chen, Lv, Peng, Wu, Xiaoliang, Liu, Jianhe, Jiang, Kehua, Lu, Hongyan, Yang, Huan, Xia, Ding, Peng, Ejun, Chen, Zhiqiang, Tang, Kun, Ye, Zhangqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667681/
https://www.ncbi.nlm.nih.gov/pubmed/33204326
http://dx.doi.org/10.7150/thno.51144