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Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice

Rationale: Mesenchymal stem cells (MSCs) show promising therapeutic potential in treating inflammatory bowel disease (IBD) due to their immunomodulatory and trophic functions. However, their efficacy is influenced by tissue origin, donator condition, isolation, and expansion methods. Here, we genera...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Wang, Xiaofang, Chen, Jiaye, Chen, Shengbo, Li, Zhijun, Liu, Hongbin, Bai, Yang, Zhi, Fachao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667691/
https://www.ncbi.nlm.nih.gov/pubmed/33204338
http://dx.doi.org/10.7150/thno.47683