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MicroRNA-15b shuttled by bone marrow mesenchymal stem cell-derived extracellular vesicles binds to WWP1 and promotes osteogenic differentiation

BACKGROUND: Osteogenic differentiation is an essential process for bone regeneration involving bone marrow mesenchymal stem cells (BMSCs). BMSC-secreted extracellular vesicles (EVs) enriched with microRNAs (miRs) have vital roles to play in mediating osteogenic differentiation. Therefore, this study...

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Detalles Bibliográficos
Autores principales: Li, Yanhong, Wang, Jing, Ma, Yanchao, Du, Wenjia, Feng, Haijun, Feng, Kai, Li, Guangjie, Wang, Shuanke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667798/
https://www.ncbi.nlm.nih.gov/pubmed/33198785
http://dx.doi.org/10.1186/s13075-020-02316-7