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Process data of allogeneic ex vivo-expanded ABCB5(+) mesenchymal stromal cells for human use: off-the-shelf GMP-manufactured donor-independent ATMP

BACKGROUND: Human dermal mesenchymal stromal cells (MSCs) expressing the ATP-binding cassette (ABC) efflux transporter ABCB5 represent an easily accessible MSC population that, based on preclinical and first-in-human data, holds significant promise to treat a broad spectrum of conditions associated...

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Detalles Bibliográficos
Autores principales: Ballikaya, Seda, Sadeghi, Samar, Niebergall-Roth, Elke, Nimtz, Laura, Frindert, Jens, Norrick, Alexandra, Stemler, Nicole, Bauer, Nicole, Rosche, Yvonne, Kratzenberg, Vanessa, Pieper, Julia, Ficek, Tina, Frank, Markus H., Ganss, Christoph, Esterlechner, Jasmina, Kluth, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667860/
https://www.ncbi.nlm.nih.gov/pubmed/33198791
http://dx.doi.org/10.1186/s13287-020-01987-y