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Microenvironmental changes induced by placenta-derived mesenchymal stem cells restore ovarian function in ovariectomized rats via activation of the PI3K-FOXO3 pathway

BACKGROUND: Translational studies have explored the therapeutic potential and feasibility of mesenchymal stem cells (MSCs) in several degenerative diseases; however, mechanistic studies of the function of these cells have been insufficient. As ovarian failure causes anovulation as well as ovarian st...

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Detalles Bibliográficos
Autores principales: Choi, Jong Ho, Seok, Jin, Lim, Seung Mook, Kim, Tae Hee, Kim, Gi Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667861/
https://www.ncbi.nlm.nih.gov/pubmed/33198818
http://dx.doi.org/10.1186/s13287-020-02002-0