OTUD7B suppresses Smac mimetic-induced lung cancer cell invasion and migration via deubiquitinating TRAF3

BACKGROUND: Smac mimetics are a type of drug that can induce apoptosis by antagonizing IAP family members in cancer treatment. However, a recent study showed that Smac mimetics can trigger cell invasion and migration in cancer cells by activating the NF-κB pathway. METHODS: We assessed lung cancer c...

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Detalles Bibliográficos
Autores principales: Zhang, Boxiang, Yang, Chengcheng, Wang, Rui, Wu, Jie, Zhang, Yunfeng, Liu, Dapeng, Sun, Xin, Li, Xiang, Ren, Hong, Qin, Sida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667862/
https://www.ncbi.nlm.nih.gov/pubmed/33198776
http://dx.doi.org/10.1186/s13046-020-01751-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667862/
https://www.ncbi.nlm.nih.gov/pubmed/33198776
http://dx.doi.org/10.1186/s13046-020-01751-3

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