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OTUD7B suppresses Smac mimetic-induced lung cancer cell invasion and migration via deubiquitinating TRAF3

BACKGROUND: Smac mimetics are a type of drug that can induce apoptosis by antagonizing IAP family members in cancer treatment. However, a recent study showed that Smac mimetics can trigger cell invasion and migration in cancer cells by activating the NF-κB pathway. METHODS: We assessed lung cancer c...

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Detalles Bibliográficos
Autores principales:	Zhang, Boxiang, Yang, Chengcheng, Wang, Rui, Wu, Jie, Zhang, Yunfeng, Liu, Dapeng, Sun, Xin, Li, Xiang, Ren, Hong, Qin, Sida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667862/ https://www.ncbi.nlm.nih.gov/pubmed/33198776 http://dx.doi.org/10.1186/s13046-020-01751-3

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