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Cold‐induced chromatin compaction and nuclear retention of clock mRNAs resets the circadian rhythm
Cooling patients to sub‐physiological temperatures is an integral part of modern medicine. We show that cold exposure induces temperature‐specific changes to the higher‐order chromatin and gene expression profiles of human cells. These changes are particularly dramatic at 18°C, a temperature synonym...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667876/ https://www.ncbi.nlm.nih.gov/pubmed/33034091 http://dx.doi.org/10.15252/embj.2020105604 |