Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Microglia are the principal phagocytes that clear cell debris in the central nervous system (CNS). This raises the question, which cells remove cell debris when microglial phagocytic activity is impaired. We addressed this question using Siglech (dtr) mice, which enable highly specific ablation of m...

Descripción completa

Detalles Bibliográficos
Autores principales: Konishi, Hiroyuki, Okamoto, Takayuki, Hara, Yuichiro, Komine, Okiru, Tamada, Hiromi, Maeda, Mitsuyo, Osako, Fumika, Kobayashi, Masaaki, Nishiyama, Akira, Kataoka, Yosky, Takai, Toshiyuki, Udagawa, Nobuyuki, Jung, Steffen, Ozato, Keiko, Tamura, Tomohiko, Tsuda, Makoto, Yamanaka, Koji, Ogi, Tomoo, Sato, Katsuaki, Kiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667883/
https://www.ncbi.nlm.nih.gov/pubmed/32959911
http://dx.doi.org/10.15252/embj.2020104464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7667883/
https://www.ncbi.nlm.nih.gov/pubmed/32959911
http://dx.doi.org/10.15252/embj.2020104464

Ejemplares similares