Cargando…

GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force

Circulating platelets roll along exposed collagen at vessel injury sites and respond with filipodia protrusion, shape change, and surface area expansion to facilitate platelet adhesion and plug formation. Various glycoproteins were considered to be both collagen responders and mediators of platelet...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeung, Jennifer, Adili, Reheman, Stringham, Emily N., Luo, Rong, Vizurraga, Alexander, Rosselli-Murai, Luciana K., Stoveken, Hannah M., Yu, Maiya, Piao, Xianhua, Holinstat, Michael, Tall, Gregory G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668045/
https://www.ncbi.nlm.nih.gov/pubmed/33097663
http://dx.doi.org/10.1073/pnas.2008921117