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GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force
Circulating platelets roll along exposed collagen at vessel injury sites and respond with filipodia protrusion, shape change, and surface area expansion to facilitate platelet adhesion and plug formation. Various glycoproteins were considered to be both collagen responders and mediators of platelet...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668045/ https://www.ncbi.nlm.nih.gov/pubmed/33097663 http://dx.doi.org/10.1073/pnas.2008921117 |