Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit

Soluble guanylate cyclase (sGC) catalyzes the conversion of guanosine triphosphate into cyclic guanosine-3′,5′-monophosphate, a key second messenger in cell signaling and tissue homeostasis. It was recently demonstrated that sGC stimulation is associated with a marked antiinflammatory effect in the...

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Detalles Bibliográficos
Autores principales: Flores-Costa, Roger, Duran-Güell, Marta, Casulleras, Mireia, López-Vicario, Cristina, Alcaraz-Quiles, José, Diaz, Alba, Lozano, Juan J., Titos, Esther, Hall, Katherine, Sarno, Renee, Masferrer, Jaime L., Clària, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668051/
https://www.ncbi.nlm.nih.gov/pubmed/33106416
http://dx.doi.org/10.1073/pnas.2000466117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668051/
https://www.ncbi.nlm.nih.gov/pubmed/33106416
http://dx.doi.org/10.1073/pnas.2000466117

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