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Metformin promotes susceptibility to experimental Leishmania braziliensis infection

BACKGROUND: Metformin (MET) is a hypoglycemic drug used for the treatment of diabetes, despite interference in host immunity against microorganisms. Cutaneous infection caused by pathogens such as Leishmania braziliensis (Lb), the agent responsible for cutaneous leishmaniasis (CL) in Brazil, represe...

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Detalles Bibliográficos
Autores principales: Lima, Filipe Rocha, Ferreira, Lais de Melo, Malta, Tainá Alves, Bonyek-Silva, Icaro, Santos, Reinan Lima, Tavares, Natália Machado, de Carvalho Filho, Edgar Marcelino, Arruda, Sérgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668079/
https://www.ncbi.nlm.nih.gov/pubmed/33206822
http://dx.doi.org/10.1590/0074-02760200272