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Evolution of regulatory signatures in primate cortical neurons at cell-type resolution

The human cerebral cortex contains many cell types that likely underwent independent functional changes during evolution. However, cell-type–specific regulatory landscapes in the cortex remain largely unexplored. Here we report epigenomic and transcriptomic analyses of the two main cortical neuronal...

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Detalles Bibliográficos
Autores principales: Kozlenkov, Alexey, Vermunt, Marit W., Apontes, Pasha, Li, Junhao, Hao, Ke, Sherwood, Chet C., Hof, Patrick R., Ely, John J., Wegner, Michael, Mukamel, Eran A., Creyghton, Menno P., Koonin, Eugene V., Dracheva, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668098/
https://www.ncbi.nlm.nih.gov/pubmed/33109720
http://dx.doi.org/10.1073/pnas.2011884117