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Efficacy of atovaquone on EpCAM(+)CD44(+) HCT-116 human colon cancer stem cells under hypoxia

Tumor hypoxia contributes to the development of resistance to chemotherapeutic drugs in several human cancer cell lines. Atovaquone, an anti-malaria drug approved by the US Food and Drug Administration, has recently demonstrated anti-cancer effects in vitro and in vivo in several cancer models. To a...

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Detalles Bibliográficos
Autores principales: Fu, Changhao, Xiao, Xu, Xu, Hao, Lu, Weifei, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668131/
https://www.ncbi.nlm.nih.gov/pubmed/33209130
http://dx.doi.org/10.3892/etm.2020.9416