Small molecule CDS-3078 induces G(2)/M phase arrest and mitochondria-mediated apoptosis in HeLa cells

The tumor suppressor p53 serves important roles in cell cycle arrest and apoptosis, and its activation increases the sensitivity of cancer cells to radiotherapy or chemotherapy. In the present study, the small molecule 2-[1-(4-(benzyloxy)phenyl)-3-oxoisoindolin-2-yl)-2-(4-methoxyphenyl)] acetic acid...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanxin, Li, Pengcheng, Rong, Jiamin, Ge, Yakun, Hu, Chenming, Bai, Xu, Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668142/
https://www.ncbi.nlm.nih.gov/pubmed/33209128
http://dx.doi.org/10.3892/etm.2020.9414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668142/
https://www.ncbi.nlm.nih.gov/pubmed/33209128
http://dx.doi.org/10.3892/etm.2020.9414

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