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Asymmetric Stratification-Induced Polarity Loss and Coordinated Individual Cell Movements Drive Directional Migration of Vertebrate Epithelium

Collective migration is essential for development, wound repair, and cancer metastasis. For most collective systems, “leader cells” determine both the direction and the power of the migration. It has remained unclear, however, how the highly polarized vertebrate epithelium migrates directionally dur...

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Detalles Bibliográficos
Autores principales: Lu, Yunzhe, Deng, Ruolan, You, Huanyang, Xu, Yishu, Antos, Christopher, Sun, Jianlong, Klein, Ophir D., Lu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668195/
https://www.ncbi.nlm.nih.gov/pubmed/33053348
http://dx.doi.org/10.1016/j.celrep.2020.108246