NineTeen Complex-subunit Salsa is required for efficient splicing of a subset of introns and dorsal–ventral patterning

The NineTeen Complex (NTC), also known as pre-mRNA-processing factor 19 (Prp19) complex, regulates distinct spliceosome conformational changes necessary for splicing. During Drosophila midblastula transition, splicing is particularly sensitive to mutations in NTC-subunit Fandango, which suggests dif...

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Detalles Bibliográficos
Autores principales: Rathore, Om Singh, Silva, Rui D., Ascensão-Ferreira, Mariana, Matos, Ricardo, Carvalho, Célia, Marques, Bruno, Tiago, Margarida N., Prudêncio, Pedro, Andrade, Raquel P., Roignant, Jean-Yves, Barbosa-Morais, Nuno L., Martinho, Rui Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668242/
https://www.ncbi.nlm.nih.gov/pubmed/32963109
http://dx.doi.org/10.1261/rna.077446.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668242/
https://www.ncbi.nlm.nih.gov/pubmed/32963109
http://dx.doi.org/10.1261/rna.077446.120

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