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The shift from early to late types of ribosomes in zebrafish development involves changes at a subset of rRNA 2′-O-Me sites

During zebrafish development, an early type of rRNA is gradually replaced by a late type that is substantially different in sequence. We applied RiboMeth-seq to rRNA from developmental stages for profiling of 2′-O-Me, to learn if changes in methylation pattern were a component of the shift. We compi...

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Detalles Bibliográficos
Autores principales: Ramachandran, Sowmya, Krogh, Nicolai, Jørgensen, Tor Erik, Johansen, Steinar Daae, Nielsen, Henrik, Babiak, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668251/
https://www.ncbi.nlm.nih.gov/pubmed/32912962
http://dx.doi.org/10.1261/rna.076760.120