Physiologic RNA targets and refined sequence specificity of coronavirus EndoU

Coronavirus EndoU inhibits dsRNA-activated antiviral responses; however, the physiologic RNA substrates of EndoU are unknown. In this study, we used mouse hepatitis virus (MHV)-infected bone marrow–derived macrophage (BMM) and cyclic phosphate cDNA sequencing to identify the RNA targets of EndoU. En...

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Detalles Bibliográficos
Autores principales: Ancar, Rachel, Li, Yize, Kindler, Eveline, Cooper, Daphne A., Ransom, Monica, Thiel, Volker, Weiss, Susan R., Hesselberth, Jay R., Barton, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668261/
https://www.ncbi.nlm.nih.gov/pubmed/32989044
http://dx.doi.org/10.1261/rna.076604.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668261/
https://www.ncbi.nlm.nih.gov/pubmed/32989044
http://dx.doi.org/10.1261/rna.076604.120

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