Interrogation of highly structured RNA with multicomponent deoxyribozyme probes at ambient temperatures

Molecular analysis of RNA through hybridization with sequence-specific probes is challenging due to the intrinsic ability of RNA molecules to form stable secondary and tertiary structures. To overcome the energy barrier toward the probe–RNA complex formation, the probes are made of artificial nucleo...

Descripción completa

Detalles Bibliográficos
Autores principales: Reed, Adam J., Sapia, Ryan J., Dowis, Charles, Solarez, Sheila, Gerasimova, Yulia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668264/
https://www.ncbi.nlm.nih.gov/pubmed/32859694
http://dx.doi.org/10.1261/rna.074864.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668264/
https://www.ncbi.nlm.nih.gov/pubmed/32859694
http://dx.doi.org/10.1261/rna.074864.120

Ejemplares similares