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Interrogation of highly structured RNA with multicomponent deoxyribozyme probes at ambient temperatures
Molecular analysis of RNA through hybridization with sequence-specific probes is challenging due to the intrinsic ability of RNA molecules to form stable secondary and tertiary structures. To overcome the energy barrier toward the probe–RNA complex formation, the probes are made of artificial nucleo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668264/ https://www.ncbi.nlm.nih.gov/pubmed/32859694 http://dx.doi.org/10.1261/rna.074864.120 |