Mechanosensitive collaboration between integrins and connexins allows nutrient and antioxidant transport into the lens

The delivery of glucose and antioxidants is vital to maintain homeostasis and lens transparency. Here, we report a new mechanism whereby mechanically activated connexin (Cx) hemichannels serve as a transport portal for delivering glucose and glutathione (GSH). Integrin α6β1 in outer cortical lens fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jie, Riquelme, Manuel A., Li, Zhen, Li, Yuting, Tong, Yuxin, Quan, Yumeng, Pei, Cheng, Gu, Sumin, Jiang, Jean X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668387/
https://www.ncbi.nlm.nih.gov/pubmed/33180092
http://dx.doi.org/10.1083/jcb.202002154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668387/
https://www.ncbi.nlm.nih.gov/pubmed/33180092
http://dx.doi.org/10.1083/jcb.202002154

Ejemplares similares