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In-vitro fragmentation of ovarian tissue activates primordial follicles through the Hippo pathway

STUDY QUESTION: What is the role of the Hippo and PI3K/Akt pathway in follicles during ovarian tissue culture in tissue derived from oncological patients and transgender men? SUMMARY ANSWER: Results highlight a Hippo pathway driven primordial follicle activation in vitro, predominantly from Day 0 to...

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Detalles Bibliográficos
Autores principales: De Roo, C, Lierman, S, Tilleman, K, De Sutter, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668399/
https://www.ncbi.nlm.nih.gov/pubmed/33225076
http://dx.doi.org/10.1093/hropen/hoaa048