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Population pharmacokinetics and dosing optimization of metformin in Chinese patients with type 2 diabetes mellitus
Approximately 35% of patients fail to attain ideal initial blood glucose control under metformin monotherapy. The objective of this observational study is to simulate the optimal protocol of metformin according to the different renal function. The population pharmacokinetics of metformin was perform...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668473/ https://www.ncbi.nlm.nih.gov/pubmed/33181704 http://dx.doi.org/10.1097/MD.0000000000023212 |