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Copper(II) Inhibition of the SARS-CoV-2 Main Protease
In an analysis of the structural stability of the coronavirus main protease (Mpro), we identified regions of the protein that could be disabled by cobalt(III)-cation binding to histidines and cysteines [1]. Here we have extended our work to include copper(II) chelates, which we have docked to HIS 41...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
ChemRxiv
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668746/ https://www.ncbi.nlm.nih.gov/pubmed/33200118 http://dx.doi.org/10.26434/chemrxiv.12673436 |