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Accounting for confounding by time, early intervention adoption, and time-varying effect modification in the design and analysis of stepped-wedge designs: Application to a proposed study design to reduce opioid-related mortality

BACKGROUND: Stepped-wedge designs (SWDs) are currently being used in the investigation of interventions to reduce opioid-related deaths in communities located in several states. However, these interventions are competing with external factors such as newly initiated public policies limiting opioid p...

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Detalles Bibliográficos
Autores principales: Rennert, Lior, Heo, Moonseong, Litwin, Alain H., De Gruttola, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668751/
https://www.ncbi.nlm.nih.gov/pubmed/33200125
http://dx.doi.org/10.21203/rs.3.rs-103992/v1