Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

Legionella pneumophila extensively modulates the host ubiquitin network to create the Legionella-containing vacuole (LCV) for its replication. Many of its virulence factors function as ubiquitin ligases or deubiquitinases (DUBs). Here, we identify Lem27 as a DUB that displays a preference for diubiq...

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Detalles Bibliográficos
Autores principales: Liu, Shuxin, Luo, Jiwei, Zhen, Xiangkai, Qiu, Jiazhang, Ouyang, Songying, Luo, Zhao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669269/
https://www.ncbi.nlm.nih.gov/pubmed/33136002
http://dx.doi.org/10.7554/eLife.58114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669269/
https://www.ncbi.nlm.nih.gov/pubmed/33136002
http://dx.doi.org/10.7554/eLife.58114

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