ASK1 Enhances Angiotensin II-Induced Liver Fibrosis In Vitro by Mediating Endoplasmic Reticulum Stress-Dependent Exosomes

BACKGROUND: Apoptosis signal-regulating kinase 1 (ASK1) has been reported to induce fibrotic signaling in the setting of oxidative stress. However, the role of ASK1 and its mechanism of action in angiotensin II- (Ang II-) induced liver fibrosis remain largely unknown. METHODS: Human hepatic LX-2 ste...

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Detalles Bibliográficos
Autores principales: Fang, Pei-pei, Pan, Chen-wei, Lin, Wei, Li, Jie, Huang, Shan-shan, Zhou, Guang-yao, Du, Wen-jun, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669360/
https://www.ncbi.nlm.nih.gov/pubmed/33223956
http://dx.doi.org/10.1155/2020/8183713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669360/
https://www.ncbi.nlm.nih.gov/pubmed/33223956
http://dx.doi.org/10.1155/2020/8183713

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