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Synergistic Effect of Pyrvinium Pamoate and Azoles Against Aspergillus fumigatus in vitro and in vivo

The effects of pyrvinium pamoate alone and in combination with azoles [itraconazole (ITC), posaconazole (POS), and voriconazole (VRC)] were evaluated against Aspergillus fumigatus both in vitro and in vivo. A total of 18 clinical strains of A. fumigatus were studied, including azole-resistant isolat...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Gao, Lujuan, Zhang, Youwen, Yang, Ji, Zeng, Tongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669749/
https://www.ncbi.nlm.nih.gov/pubmed/33224118
http://dx.doi.org/10.3389/fmicb.2020.579362