Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder Inhalers

Metformin is an activator of the AMPK and Nrf2 pathways which are important in the pathology of several complex pulmonary diseases with unmet medical needs. Organic solution advanced spray drying in the absence of water in closed-mode was used to design and develop respirable dry powders. Following...

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Detalles Bibliográficos
Autores principales: Acosta, Maria F., Abrahamson, Michael D., Encinas-Basurto, David, Fineman, Jeffrey R., Black, Stephen M., Mansour, Heidi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669792/
https://www.ncbi.nlm.nih.gov/pubmed/33200330
http://dx.doi.org/10.1208/s12248-020-00531-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669792/
https://www.ncbi.nlm.nih.gov/pubmed/33200330
http://dx.doi.org/10.1208/s12248-020-00531-3

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