Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis

Skeletal muscle promotes metabolic balance by regulating glucose uptake and the stimulation of multiple interorgan crosstalk. We show here that the catalytic activity of Vav2, a Rho GTPase activator, modulates the signaling output of the IGF1- and insulin-stimulated phosphatidylinositol 3-kinase pat...

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Detalles Bibliográficos
Autores principales: Rodríguez-Fdez, Sonia, Lorenzo-Martín, L. Francisco, Fernández-Pisonero, Isabel, Porteiro, Begoña, Veyrat-Durebex, Christelle, Beiroa, Daniel, Al-Massadi, Omar, Abad, Antonio, Diéguez, Carlos, Coppari, Roberto, Nogueiras, Rubén, Bustelo, Xosé R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669868/
https://www.ncbi.nlm.nih.gov/pubmed/33199701
http://dx.doi.org/10.1038/s41467-020-19489-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669868/
https://www.ncbi.nlm.nih.gov/pubmed/33199701
http://dx.doi.org/10.1038/s41467-020-19489-z

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