Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

The ATP-gated P2X7 receptor is highly expressed in microglia and has been involved in diverse brain diseases. P2X7 effects were also described in neurons and astrocytes but its localisation and function in these cell types has been challenging to demonstrate in situ. BAC transgenic mouse lines have...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramírez-Fernández, Antonio, Urbina-Treviño, Lidia, Conte, Giorgia, Alves, Mariana, Rissiek, Björn, Durner, Anna, Scalbert, Nicolas, Zhang, Jiong, Magnus, Tim, Koch-Nolte, Friedrich, Plesnila, Nikolaus, Deussing, Jan M., Engel, Tobias, Kopp, Robin, Nicke, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669894/
https://www.ncbi.nlm.nih.gov/pubmed/33199725
http://dx.doi.org/10.1038/s41598-020-76428-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669894/
https://www.ncbi.nlm.nih.gov/pubmed/33199725
http://dx.doi.org/10.1038/s41598-020-76428-0

Ejemplares similares